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Article

Integrating germline and somatic data towards a personalized cancer medicine.

Trends in molecular medicine - 1 Aug 2014

Pujana Miguel Angel

Abstract excerpt

In recent years there have been major advances in the knowledge of the genetic alterations that drive cancer susceptibility and progression. However, the molecular links between these alteration levels (i.e., germline for susceptibility and somatic for progression) remain mostly unknown. Here, the potential of integrating germline and somatic data for a comprehensive and personalized cancer medicine is discussed.

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Identifiers

PMID: 25086750
DOI: 10.1016/j.molmed.2014.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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