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Biology of Cancer and Aging: A Complex Association With Cellular Senescence

29 Jul 2014

Abstract excerpt

Over the last 50 years, major improvements have been made in our understanding of the driving forces, both parallel and opposing, that lead to aging and cancer. Many theories on aging first proposed in the 1950s, including those associated with telomere biology, senescence, and adult stem-cell regulation, have since gained support from cumulative experimental evidence. These views suggest that the accumulation of...

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PMID: 25071126
DOI: 10.1200/jco.2014.55.1432

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