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Concise Review: MicroRNA Expression in Multipotent Mesenchymal Stromal Cells

8 Nov 2007

Abstract excerpt

Mesenchymal stem cells, or multipotent mesenchymal stromal cells (MSC), isolated from various adult tissue sources have the capacities to self-renew and to differentiate into multiple lineages. Both of these processes are tightly regulated by genetic and epigenetic mechanisms. Emerging evidence indicates that the class of single-stranded noncoding RNAs known as microRNAs also plays a critical role in this...

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PMID: 17991914
DOI: 10.1634/stemcells.2007-0625

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