Article
Clinical and pharmacogenomic implications of genetic variation in a Southern Ethiopian population.
The pharmacogenomics journal - 1 Feb 2015
Tekola-Ayele Fasil, Adeyemo Adebowale, Aseffa Abraham, Hailu Elena, Finan Chris, Davey Gail, Rotimi Charles N, Newport Melanie J
Abstract excerpt
Africa is home to genetically diverse human populations. We compared the genetic structure of the Wolaita ethnic population from Southern Ethiopia (WETH, n=120) with HapMap populations using genome-wide variants. We investigated allele frequencies of 443 clinically and pharmacogenomically relevant genetic variants in WETH compared with HapMap populations. We found that WETH were genetically most similar to the...
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