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Cell-Free Fetal Nucleic Acid Testing: A Review of the Technology and Its Applications

1 Jul 2011

Abstract excerpt

UNLABELLED: Cell-free fetal nucleic acids circulating in the blood of pregnant women afford the opportunity for early, noninvasive prenatal genetic testing. The predominance of admixed maternal genetic material in circulation demands innovative means for identification and analysis of cell-free fetal DNA and RNA. Techniques using polymerase chain reaction, mass spectrometry, and sequencing have been developed for...

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PMID: 21944155
DOI: 10.1097/ogx.0b013e31822dfbe2

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