Up Regulation of Liver‐enriched Transcription Factors <scp>HNF</scp>4a and <scp>HNF</scp>6 and Liver‐Specific Micro<scp>RNA</scp> (miR‐122) by Inhibition of Let‐7b in Mesenchymal Stem Cells

Abstract excerpt

MicroRNAs are small non-coding RNAs that regulate key processes of the stem cells. Although, microRNAs have emerged as powerful regulators of differentiation, few studies have been focused on the post-transcriptional regulation of hepatic differentiation in mesenchymal stem cells (MSCs) by microRNAs. The aim of this study was to evaluate the specific effect of let-7 microRNAs in particular let-7b in hepatic...

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