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Article

Bcl-2-like protein 11 deletion polymorphism predicts survival in advanced non-small-cell lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Sept 2014

Lee Jih-Hsiang, Lin Yu-Lin, Hsu Wei-Hsun, Chen Hsuan-Yu, Chang Yeun-Chung, Yu Chong-Jen, Shih Jin-Yuan, Lin Chia-Chi, Chen Kuan-Yu, Ho Chao-Chi, Laio Wei-Yu, Yang Pan-Chyr, Yang James Chih-Hsin

Abstract excerpt

INTRODUCTION: Germline Bcl-2-like protein 11 (BIM) deletion polymorphism in Asian is a poor predictive factor for treatment outcomes to tyrosine kinase inhibitors (TKIs) in malignancies. We explored the impact of BIM deletion polymorphism on treatment outcome of advanced non-small-cell lung cancer (NSCLC). METHODS: We prospectively collected tissue samples, blood, and clinical data from two cohorts of advanced...

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Identifiers

PMID: 25057939
DOI: 10.1097/JTO.0000000000000238

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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