Article
Vibrio cholerae utilizes direct sRNA regulation in expression of a biofilm matrix protein.
PloS one - 1 Jan 2014
Song Tianyan, Sabharwal Dharmesh, Gurung Jyoti Mohan, Cheng Andrew T, Sjöström Annika E, Yildiz Fitnat H, Uhlin Bernt Eric, Wai Sun Nyunt
Abstract excerpt
Vibrio cholerae biofilms contain exopolysaccharide and three matrix proteins RbmA, RbmC and Bap1. While much is known about exopolysaccharide regulation, little is known about the mechanisms by which the matrix protein components of biofilms are regulated. VrrA is a conserved, 140-nt sRNA of V. cholerae, whose expression is controlled by sigma factor σE. In this study, we demonstrate that VrrA negatively...
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