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Article

MicroRNA-340 as a modulator of RAS-RAF-MAPK signaling in melanoma.

Archives of biochemistry and biophysics - 1 Dec 2014

Poenitzsch Strong Ashley M, Setaluri Vijayasaradhi, Spiegelman Vladimir S

Abstract excerpt

microRNA (miRNA)-dependent regulation of gene expression is increasingly linked to development and progression of melanoma. In this study we evaluated the functions of miR-340 in human melanoma cells. Here, we show that miR-340 inhibits the tumorigenic phenotype of melanoma cells. We also found that miR-340 regulates RAS-RAF-Mitogen Activated Protein Kinase (MAPK) signaling by modulating the expression of...

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Share to Cell Line, Tumor
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

Share to MAP Kinase Signaling System

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Source

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Identifiers

PMID: 25043973
DOI: 10.1016/j.abb.2014.07.012
PMCID: PMC4221550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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