Article
Mitochondrial DNA haplogroups are associated with severe sepsis and mortality in patients who underwent major surgery.
The Journal of infection - 1 Jan 2015
Jiménez-Sousa Maria Angeles, Tamayo Eduardo, Guzmán-Fulgencio María, Heredia María, Fernández-Rodríguez Amanda, Gómez Esther, Almansa Raquel, Gómez-Herreras José I, García-Álvarez Mónica, Gutiérrez-Junco Sandra, Bermejo-Martin Jesús F, Resino Salvador
Abstract excerpt
OBJECTIVE: To analyse whether mitochondrial DNA (mtDNA) haplogroups are associated with severe sepsis and mortality after major surgery. METHODS: We performed a case-control study on 240 cardiac or abdominal surgery patients developing severe sepsis (Case-group) and 267 cardiac or abdominal surgery patients without severe sepsis and with systemic inflammatory response syndrome (SIRS, Control-group). Furthermore,...
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