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Use of plasma mitochondrial DNA levels for determining disease severity and prognosis in pediatric sepsis: a case control study

9 Aug 2018

Abstract excerpt

BACKGROUND: The mortality rate due to severe sepsis is approximately 30-60%. Sepsis readily progresses to septic shock and multiple organ dysfunction, representing a significant problem in the pediatric intensive care unit (PICU). The aim of this study was to explore the value of plasma mitochondrial DNA (mtDNA) for early diagnosis and prognosis in children with sepsis. METHODS: A total of 123 children with...

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PMID: 30092777
DOI: 10.1186/s12887-018-1239-z

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