Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel and functional DNA sequence variants within the GATA6 gene promoter in ventricular septal defects.

International journal of molecular sciences - 17 Jul 2014

Li Chunyu, Li Xianke, Pang Shuchao, Chen Wei, Qin Xianyun, Huang Wenhui, Zeng Changqing, Yan Bo

Abstract excerpt

Congenital heart disease (CHD) is the most common birth defect in humans. Genetic causes and underlying molecular mechanisms for isolated CHD remain largely unknown. Studies have demonstrated that GATA transcription factor 6 (GATA6) plays an essential role in the heart development. Mutations in GATA6 gene have been associated with diverse types of CHD. As GATA6 functions in a dosage-dependent manner, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GATA6 Transcription Factor

Share to Heart Septal Defects, Ventricular

Share to Infant

Share to Myocytes, Cardiac

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 25036032
DOI: 10.3390/ijms150712677
PMCID: PMC4139867

Genes

GATA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel and functional DNA sequence variants within the GATA6 gene promoter in ventricular septal defects.PMID 25036032Read ↗

Novel and functional DNA sequence variants within the GATA5 gene promoter in ventricular septal defects.Semantic proximity Read ↗

A novel GATA6 mutation associated with congenital ventricular septal defect.Semantic proximity Read ↗

Identification and functional analysis of variants of MYH6 gene promoter in isolated ventricular septal defectsSemantic proximity Read ↗

Novel GATA6 mutations associated with congenital ventricular septal defect or tetralogy of fallot.Semantic proximity Read ↗

Novel and functional sequence variants within the TBX2 gene promoter in ventricular septal defects.Semantic proximity Read ↗

A novel GATA4 mutation responsible for congenital ventricular septal defects.Semantic proximity Read ↗

Two functional sequence variants of the GATA6 gene promoter in patients with indirect inguinal hernia.Semantic proximity Read ↗

Novel and functional variants within the TBX18 gene promoter in ventricular septal defects.Semantic proximity Read ↗

A novel GATA6 mutation in patients with tetralogy of Fallot or atrial septal defect.Semantic proximity Read ↗

A novel GATA4 loss-of-function mutation associated with congenital ventricular septal defect.Semantic proximity Read ↗

A case of 46,XY disorders of sex development with congenital heart disease caused by a GATA4 variant.Semantic proximity Read ↗

Identification of GATA6 sequence variants in patients with congenital heart defects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.