Article
A novel GATA4 mutation responsible for congenital ventricular septal defects.
International journal of molecular medicine - 1 Oct 2011
Wang Juan, Fang Ming, Liu Xing-Yuan, Xin Yuan-Feng, Liu Zhong-Min, Chen Xiao-Zhong, Wang Xiao-Zhou, Fang Wei-Yi, Liu Xu, Yang Yi-Qing
Abstract excerpt
Ventricular septal defect (VSD) is the most common type of cardiovascular developmental anomaly and is an important risk factor for the substantially increased morbidity and mortality in newborns. Aggregating evidence implicates genetic defects in the pathogenesis of congenital VSD. However, VSD is genetically heterogeneous and the genetic determinants for VSD in most patients remain to be identified. In this...
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