Article
A novel GATA4 loss-of-function mutation associated with congenital ventricular septal defect.
Pediatric cardiology - 1 Apr 2012
Yang Yi-Qing, Li Li, Wang Juan, Liu Xing-Yuan, Chen Xiao-Zhong, Zhang Wei, Wang Xiao-Zhou, Jiang Jin-Qi, Liu Xu, Fang Wei-Yi
Abstract excerpt
Ventricular septal defect (VSD) is the most prevalent type of congenital heart disease and a major cause for the significantly increased morbidity and mortality among infants. Aggregating evidence indicates that genetic defects are involved in the pathogenesis of congenital VSD. Nevertheless, VSD is genetically heterogeneous, and the genetic determinants for VSD in the majority of patients remain to be...
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