Article
Role of estrogen related receptor beta (ESRRB) in DFN35B hearing impairment and dental decay.
BMC medical genetics - 15 Jul 2014
Weber Megan L, Hsin Hong-Yuan, Kalay Ersan, BroŽková Dana S, Shimizu Takehiko, Bayram Merve, Deeley Kathleen, Küchler Erika C, Forella Jessalyn, Ruff Timothy D, Trombetta Vanessa M, Sencak Regina C, Hummel Michael, Briseño-Ruiz Jessica, Revu Shankar K, Granjeiro José M, Antunes Leonardo S, Antunes Livia A, Abreu Fernanda V, Costa Marcelo C, Tannure Patricia N, Koruyucu Mine, Patir Asli, Poletta Fernando A, Mereb Juan C, Castilla Eduardo E, Orioli Iêda M, Marazita Mary L, Ouyang Hongjiao, Jayaraman Thottala, Seymen Figen, Vieira Alexandre R
Abstract excerpt
BACKGROUND: Congenital forms of hearing impairment can be caused by mutations in the estrogen related receptor beta (ESRRB) gene. Our initial linkage studies suggested the ESRRB locus is linked to high caries experience in humans. METHODS: We tested for association between the ESRRB locus and dental caries in 1,731 subjects, if ESRRB was expressed in whole saliva, if ESRRB was associated with the microhardness of...
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