Article
A polymorphism in human estrogen-related receptor beta (ESRRβ) predicts audiometric temporary threshold shift.
International journal of audiology - 1 Oct 2016
Bhatt Ishan, Phillips Susan, Richter Scott, Tucker Denise, Lundgren Kristine, Morehouse Robin, Henrich Vincent
Abstract excerpt
OBJECTIVE: A non-synonymous single nucleotide polymorphism (rs61742642; C to T, P386S) in the ligand-binding domain of human estrogen-related receptor beta (ESRRβ) showed possible association to noise-induced hearing loss (NIHL) in our previous study. DESIGN: This study was conducted to examine the effect of the ESRRβ rs61742642 T variant on temporary threshold shift (TTS). TTS was induced by 10 minutes of...
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