Article
Massive dissemination from spinal cord gangliogliomas negative for BRAF V600E: report of two rare adult cases.
American journal of clinical pathology - 1 Aug 2014
Lummus Seth C, Aisner Dara L, Sams Sharon B, Foreman Nicholas K, Lillehei Kevin O, Kleinschmidt-DeMasters B K
Abstract excerpt
OBJECTIVES: Metastatic leptomeningeal spread from spinal cord gangliogliomas (GGs) is exceedingly rare. METHODS: Two adult women, aged 27 and 51 years, died of massive disseminations of cervicothoracic GGs 4 and 6 years, respectively, after initial diagnoses; full autopsies were performed. BRAF status was assessed by VE1 immunohistochemistry (IHC), Sanger sequencing, and a single-nucleotide base extension assay...
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