Article
NRAS(Q61K) mutated primary leptomeningeal melanoma in a child: case presentation and discussion on clinical and diagnostic implications.
BMC cancer - 20 Jul 2016
Angelino Giulia, De Pasquale Maria Debora, De Sio Luigi, Serra Annalisa, Massimi Luca, De Vito Rita, Marrazzo Antonio, Lancella Laura, Carai Andrea, Antonelli Manila, Giangaspero Felice, Gessi Marco, Menchini Laura, Scarciolla Laura, Longo Daniela, Mastronuzzi Angela
Abstract excerpt
BACKGROUND: Primary melanocytic neoplasms are rare in the pediatric age. Among them, the pattern of neoplastic meningitis represents a peculiar diagnostic challenge since neuroradiological features may be subtle and cerebrospinal fluid analysis may not be informative. Clinical misdiagnosis of neoplastic meningitis with tuberculous meningitis has been described in few pediatric cases, leading to a significant...
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