Article
Occurrence of diverse mutations in isoniazid- and rifampicin-resistant Mycobacterium tuberculosis isolates from autochthonous and immigrant populations of Saudi Arabia.
Microbial drug resistance (Larchmont, N.Y.) - 1 Dec 2014
Varghese Bright, Shoukri Mohammed, Memish Ziad, Abuljadayel Naila, Alhakeem Raafat, Alrabiah Fahad, Al-Hajoj Sahal
Abstract excerpt
For the first time in Saudi Arabia, the impact of a patient's ethnic background on mutations conferring resistance to rifampicin (RIF) and isoniazid (INH) in Mycobacterium tuberculosis isolates was analyzed on a nationwide sample collection. Four hundred fifteen isolates were subjected to drug susceptibility testing, mutation analysis, spoligotyping, and 24 loci-based Mycobacterial Interspersed Repetitive...
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