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Article

Altered expression pattern of miR-29a, miR-29b and the target genes in myeloid leukemia

1 Jul 2014

Abstract excerpt

OBJECTIVES: The miR-29 family have been demonstrated acting as vital tumor suppressor in multiple cancers as well as regulators in the adaptive immune system. Little is known about their role in leukemogenesis. The purpose of this study is to analyze the expression pattern of miR-29a/29b and its target genes Mcl-1 (myeloid cell leukemia sequence 1) and B-cell lymphoma 2 (Bcl-2) in myeloid leukemia. METHODS:...

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PMID: 25006537
DOI: 10.1186/2162-3619-3-17

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