Article

A standardized gnotobiotic mouse model harboring a minimal 15-member mouse gut microbiota recapitulates SOPF/SPF phenotypes

2019-12-30

Abstract excerpt

Mus musculus is the classic mammalian model for biomedical research. Despite global efforts to standardize breeding and experimental procedures, the undefined composition and interindividual diversity of the microbiota of laboratory mice remains a limitation. In an attempt to standardize the gut microbiome in preclinical mouse studies, we developed a simplified mouse microbiota composed of 15 strains from 7 of the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bf248692-9f05-50b3-b849-6048f3cb2d52
DOI: 10.1101/2019.12.30.890954

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A standardized gnotobiotic mouse model harboring a minimal 15-member mouse gut microbiota recapitulates SOPF/SPF phenotypesDOI 10.1101/2019.12.30.890954Read

A standardized gnotobiotic mouse model harboring a minimal 15-member mouse gut microbiota recapitulates SOPF/SPF phenotypes.Semantic proximity Read

Gnotobiotic and Conventional Mouse Systems to Support Microbiota Based StudiesSemantic proximity Read

A guide to germ‐free and gnotobiotic mouse technology to study health and diseaseSemantic proximity Read

Introducing Murine Microbiome Database (MMDB): A Curated Database with Taxonomic Profiling of the Healthy Mouse Gastrointestinal MicrobiomeSemantic proximity Read

How informative is the mouse for human gut microbiota research?Semantic proximity Read

The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiotaSemantic proximity Read

Constructing a gnotobiotic mouse model with a synthetic human gut microbiome to study host–microbe cross talkSemantic proximity Read

The Mouse Gut Microbial Biobank expands the coverage of cultured bacteriaSemantic proximity Read

Characteristics of gut microbiota in representative mice strains: Implications for biological researchSemantic proximity Read

Effects of Vendor and Genetic Background on the Composition of the Fecal Microbiota of Inbred MiceSemantic proximity Read

Natural versus Laboratory World: Incorporating Wild-Derived Microbiota into Preclinical Rodent ModelsSemantic proximity Read

The Altered Schaedler Flora: Continued Applications of a Defined Murine Microbial CommunitySemantic proximity Read