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Article

Association of exceptional parental longevity and physical function in aging.

Age (Dordrecht, Netherlands) - 1 Jan 2014

Ayers Emmeline, Barzilai Nir, Crandall Jill P, Milman Sofiya, Verghese Joe

Abstract excerpt

Offspring of parents with exceptional longevity (OPEL), who are more likely to carry longevity-associated genotypes, may age more successfully than offspring of parents with usual survival (OPUS). Maintenance of physical function is a key attribute of successful aging. While many genetic and non-genetic factors interact to determine physical phenotype in aging, examination of the contribution of exceptional...

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Identifiers

PMID: 24997018
DOI: 10.1007/s11357-014-9677-5
PMCID: PMC4150888

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