Article
Gatekeeper tyrosine phosphorylation is autoinhibitory for Symbiosis Receptor Kinase.
FEBS letters - 25 Aug 2014
Paul Anindita, Samaddar Sandip, Bhattacharya Avisek, Banerjee Anindyajit, Das Abhishek, Chakrabarti Saikat, DasGupta Maitrayee
Abstract excerpt
Plant receptor-like kinases (RLKs) are distinguished by having a tyrosine in the 'gatekeeper' position. Previously we reported Symbiosis Receptor Kinase from Arachis hypogaea (AhSYMRK) to autophosphorylate on the gatekeeper tyrosine (Y670), though this phosphorylation was not necessary for the kinase activity. Here we report that recombinant catalytic domain of AhSYMRK with a phosphomimic substitution in the...
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