Article
CTL responses to DCs stimulated with leishmania antigens detected by DCs expressing Leishmania gp63.
Iranian journal of immunology : IJI - 1 Jun 2014
Rezvan Hossein, Khodadadi Ali, Ali Selman A
Abstract excerpt
BACKGROUND: Leishmania is a pathogenic parasite which infects mononuclear cells in vertebrate hosts. Different strategies have been taken to develop immunity against Leishmania. DCs loaded with immunogenic antigen have resulted in different levels of Th1-type immune response and cytotoxic T lymphocytes (CTL) activity. OBJECTIVE: To evaluate the potency of DCs primed with soluble Leishmania mexicana antigens (SLA)...
Topics
- Animals
- Antigens, Protozoan
- Antigens, Surface
- Cytotoxicity, Immunologic
- Dendritic Cells
- Gene Expression
- Immunophenotyping
- Leishmania
- Leishmaniasis
- Metalloendopeptidases
- Mice
