Article
Development of [(11)C]erlotinib positron emission tomography for in vivo evaluation of EGF receptor mutational status.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2013
Bahce Idris, Smit Egbert F, Lubberink Mark, van der Veldt Astrid A M, Yaqub Maqsood, Windhorst Albert D, Schuit Robert C, Thunnissen Erik, Heideman Daniëlle A M, Postmus Pieter E, Lammertsma Adriaan A, Hendrikse N Harry
Abstract excerpt
PURPOSE: To evaluate whether, in patients with non-small cell lung carcinoma (NSCLC), tumor uptake of [(11)C]erlotinib can be quantified and imaged using positron emission tomography and to assess whether the level of tracer uptake corresponds with the presence of activating tumor EGF receptor (E...
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