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Article

Prognostic impact of [18F]fluorothymidine and [18F]fluoro-D-glucose baseline uptakes in patients with lung cancer treated first-line with erlotinib.

PloS one - 1 Jan 2013

Scheffler Matthias, Zander Thomas, Nogova Lucia, Kobe Carsten, Kahraman Deniz, Dietlein Markus, Papachristou Irini, Heukamp Lukas, Büttner Reinhard, Boellaard Ron, Lammertsma Adriaan A, Querings Silvia, Stoelben Erich, Engel-Riedel Walburga, Neumaier Bernd, Wolf Jürgen

Abstract excerpt

UNLABELLED: 3'-deoxy-3'-[(18)F]fluoro-L-thymidine (FLT) and 2'-deoxy-2'-[(18)F]fluoro-D-glucose (FDG) are used to visualize proliferative and metabolic activity of tumors. In this study we aimed at evaluating the prognostic value of FLT and FDG uptake measured by positron emission tomography (PET) in patients with metastatic non-small cell lung cancer (NSCLC) prior to systemic therapy with erlotinib. FLT and FDG...

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Identifiers

PMID: 23308140
DOI: 10.1371/journal.pone.0053081
PMCID: PMC3537767

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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