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Article

Feasibility of Early Dynamic 18F-FDG PET/CT Imaging for Predicting EGFR and TP53 Mutations in Lung Adenocarcinoma.

Molecular imaging and biology - 1 Dec 2025

Zhang Ying, Liu Guobing, Guan Yingying, Li Beilei, Zhang Yiqiu

Abstract excerpt

OBJECTIVE: To investigate the feasibility of early dynamic 2-[18F]-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) imaging in predicting epidermal growth factor receptor (EGFR) and tumor protein 53 (TP53) mutation status in lung adenocarcinoma (AC). METHODS: In total, 81 patients with lung nodules underwent early dynamic PET (10 min after injection) and late static PET...

Read the complete abstract on PubMed

Topics

Humans
Male
Female
Middle Aged
Fluorodeoxyglucose F18
Positron Emission Tomography Computed Tomography

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

ErbB Receptors

Mutation

Tumor Suppressor Protein p53

Adenocarcinoma of Lung

Feasibility Studies

Lung Neoplasms

Aged

ROC Curve

Source

Identifiers

PMID: 41239154
DOI: 10.1007/s11307-025-02059-4

Genes

EGFR
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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