Article
Biased hypermutation occurred frequently in a gene inserted into the IC323 recombinant measles virus during its persistence in the brains of nude mice.
Virology - 1 Aug 2014
Otani Sanae, Ayata Minoru, Takeuchi Kaoru, Takeda Makoto, Shintaku Haruo, Ogura Hisashi
Abstract excerpt
Measles virus (MV) is the causative agent of measles and its neurological complications, subacute sclerosing panencephalitis (SSPE) and measles inclusion body encephalitis (MIBE). Biased hypermutation in the M gene is a characteristic feature of SSPE and MIBE. To determine whether the M gene is t...
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