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Article

Within-host evolution of Burkholderia pseudomallei in four cases of acute melioidosis.

PLoS pathogens - 15 Jan 2010

Price Erin P, Hornstra Heidie M, Limmathurotsakul Direk, Max Tamara L, Sarovich Derek S, Vogler Amy J, Dale Julia L, Ginther Jennifer L, Leadem Benjamin, Colman Rebecca E, Foster Jeffrey T, Tuanyok Apichai, Wagner David M, Peacock Sharon J, Pearson Talima, Keim Paul

Abstract excerpt

Little is currently known about bacterial pathogen evolution and adaptation within the host during acute infection. Previous studies of Burkholderia pseudomallei, the etiologic agent of melioidosis, have shown that this opportunistic pathogen mutates rapidly both in vitro and in vivo at tandemly...

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Identifiers

PMID: 20090837
DOI: 10.1371/journal.ppat.1000725
PMCID: PMC2799673

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20090837-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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