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Article

Logic programming to predict cell fate patterns and retrodict genotypes in organogenesis.

Journal of the Royal Society, Interface - 6 Sept 2014

Hall Benjamin A, Jackson Ethan, Hajnal Alex, Fisher Jasmin

Abstract excerpt

Caenorhabditis elegans vulval development is a paradigm system for understanding cell differentiation in the process of organogenesis. Through temporal and spatial controls, the fate pattern of six cells is determined by the competition of the LET-23 and the Notch signalling pathways. Modelling cell fate determination in vulval development using state-based models, coupled with formal analysis techniques, has...

Topics

Algorithms
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Lineage
ErbB Receptors
Female
Genome, Helminth
Genotype
Models, Genetic
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Organogenesis

Receptors, Notch

Signal Transduction

Time Factors

Vulva

Source

Open in PubMed Open full text

Identifiers

PMID: 24966232
DOI: 10.1098/rsif.2014.0245
PMCID: PMC4233684

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24966232-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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