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Article

Logic programming to predict cell fate patterns and retrodict genotypes in organogenesis.

Journal of the Royal Society, Interface - 6 Sept 2014

Hall Benjamin A, Jackson Ethan, Hajnal Alex, Fisher Jasmin

Abstract excerpt

Caenorhabditis elegans vulval development is a paradigm system for understanding cell differentiation in the process of organogenesis. Through temporal and spatial controls, the fate pattern of six cells is determined by the competition of the LET-23 and the Notch signalling pathways. Modelling cell fate determination in vulval development using state-based models, coupled with formal analysis techniques, has...

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Identifiers

PMID: 24966232
DOI: 10.1098/rsif.2014.0245
PMCID: PMC4233684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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