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Article

Low back and common widespread pain share common genetic determinants.

Annals of human genetics - 1 Sept 2014

Malkin Ida, Williams Frances M K, LaChance Genevieve, Spector Timothy, MacGregor Alex J, Livshits Gregory

Abstract excerpt

Low back (LBP) and chronic widespread musculoskeletal pain (CWP) both have a significant genetic component and are associated with increased body mass index (BMI). We examined whether LBP and CWP share common genetic factors, and to what extent this correlation is modified by the genetic factors influencing BMI. Genetic analysis of binary traits such as pain is not simple, particularly if their risk is associated...

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Identifiers

PMID: 24962672
DOI: 10.1111/ahg.12074

Genes

LBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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