Article
Genetic and environmental influences on non-specific low back pain in children: a twin study.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society - 1 Apr 2008
El-Metwally Ashraf, Mikkelsson Marja, Ståhl Minna, Macfarlane Gary J, Jones Gareth T, Pulkkinen Lea, Rose Richard J, Kaprio Jaakko
Abstract excerpt
Aggregation of low back symptoms in families of children with low back pain (LBP) has been described. However, this may be due to genetic factors or common exposure to environmental factors. The aim of this study was to evaluate the relative contribution of genetic and environmental factors to childhood LBP by comparing the pairwise similarity of LBP in pairs of monozygotic (MZ) and dizygotic (DZ) twin children....
Topics
- Biometry
- Child
- Environment
- Female
- Genetic Predisposition to Disease
- Health Surveys
- Humans
- Low Back Pain
- Male
- Models, Genetic