Article
BMP-2, hypoxia, and COL1A1/HtrA1 siRNAs favor neo-cartilage hyaline matrix formation in chondrocytes.
Tissue engineering. Part C, Methods - 1 Feb 2015
Ollitrault David, Legendre Florence, Drougard Carole, Briand Mélanie, Benateau Hervé, Goux Didier, Chajra Hanane, Poulain Laurent, Hartmann Daniel, Vivien Denis, Shridhar Vijayalakshmi, Baldi Alfonso, Mallein-Gerin Frédéric, Boumediene Karim, Demoor Magali, Galera Philippe
Abstract excerpt
Osteoarthritis (OA) is an irreversible pathology that causes a decrease in articular cartilage thickness, leading finally to the complete degradation of the affected joint. The low spontaneous repair capacity of cartilage prevents any restoration of the joint surface, making OA a major public hea...
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