Article
Exploring effects of EAAT polymorphisms on cognitive functions in schizophrenia.
Pharmacogenomics - 1 May 2014
Spangaro Marco, Bosia Marta, Zanoletti Andrea, Bechi Margherita, Mariachiara Buonocore, Pirovano Adele, Lorenzi Cristina, Bramanti Placido, Smeraldi Enrico, Cavallaro Roberto
Abstract excerpt
AIM: To evaluate the effect of functional polymorphisms (rs4354668 and rs2731880) of the excitatory amino acid transporters (EAAT1 and 2) on the cognitive dysfunction that characterizes schizophrenia. MATERIALS & METHODS: One hundred and ninety two subjects diagnosed with schizophrenia were assessed with Brief Assessment of Cognition in Schizophrenia, Wisconsin Card Sorting Test, Continuous Performance Test and...
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