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Article

Genetic epidemiology of cancer predisposition DNA repair genes is probably related with ancestral surviving under adverse environmental conditions.

Genetic testing and molecular biomarkers - 1 Aug 2014

Voskarides Konstantinos

Abstract excerpt

AIMS: Surviving under a stressful environment may be a real challenge. Individuals (and their offspring) with accumulated genetic variation in their DNA repair genes may have a higher probability to survive under these conditions. A partially unstable DNA repair system raises the mutagenesis rate and the probability for an advantageous mutation to appear. This can also explain the high incidence of specific types...

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PMID: 24933130
DOI: 10.1089/gtmb.2014.0053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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