Article
Antiretroviral therapy modifies the genetic effect of known type 2 diabetes-associated risk variants in HIV-infected women.
AIDS (London, England) - 31 Jul 2014
Frasco Melissa A, Karim Roksana, Van Den Berg David, Watanabe Richard M, Anastos Kathryn, Cohen Mardge, Gange Stephen J, Gustafson Deborah R, Liu Chenglong, Tien Phyllis C, Mack Wendy J, Pearce Celeste L
Abstract excerpt
OBJECTIVE: Type 2 diabetes mellitus incidence is increased in HIV-infected persons. We examined the associations of diabetes mellitus with known diabetes mellitus-risk alleles from the general population in the context of HIV infection, and explored effect modification by combination antiretroviral therapy (cART). METHODS: The Women's Interagency HIV Study is a prospective cohort of HIV-infected women. Seventeen...
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