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Article

CEACAM1 promotes melanoma cell growth through Sox-2.

Neoplasia (New York, N.Y.) - 1 May 2014

Ortenberg Rona, Galore-Haskel Gilli, Greenberg Ilanit, Zamlin Bella, Sapoznik Sivan, Greenberg Eyal, Barshack Iris, Avivi Camila, Feiler Yulia, Zan-Bar Israel, Besser Michal J, Azizi Ester, Eitan Friedman, Schachter Jacob, Markel Gal

Abstract excerpt

The prognostic value of the carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1) in melanoma was demonstrated more than a decade ago as superior to Breslow score. We have previously shown that intercellular homophilic CEACAM1 interactions protect melanoma cells from lymphocyte-mediated elimination. Here, we study the direct effects of CEACAM1 on melanoma cell biology. By employing tissue microarrays and...

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Source

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Identifiers

PMID: 24931667
DOI: 10.1016/j.neo.2014.05.003
PMCID: PMC4198694

Genes

CEACAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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