Article
Model-independent fluxome profiling from 2H and 13C experiments for metabolic variant discrimination.
Genome biology - 1 Jan 2004
Zamboni Nicola, Sauer Uwe
Abstract excerpt
We introduce a conceptually novel method for intracellular fluxome profiling from unsupervised statistical analysis of stable isotope labeling. Without a priori knowledge on the metabolic system, we identified characteristic flux fingerprints in 10 Bacillus subtilis mutants from 132 2H and 13C tr...
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