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Article

GNAS is frequently mutated in both low-grade and high-grade disseminated appendiceal mucinous neoplasms but does not affect survival.

Human pathology - 1 Aug 2014

Singhi Aatur D, Davison Jon M, Choudry Haroon A, Pingpank James F, Ahrendt Steven A, Holtzman Matthew P, Zureikat Amer H, Zeh Herbert J, Ramalingam Lekshmi, Mantha Geeta, Nikiforova Marina, Bartlett David L, Pai Reetesh K

Abstract excerpt

We analyzed a series of 55 disseminated appendiceal mucinous neoplasms treated at our institution for GNAS and KRAS mutations in an attempt to correlate mutation status with clinicopathological findings and patient survival. GNAS mutations (p.R201H, c.602G>A and p.R201C, and c.602C>T) were identified in 17 (31%) of 55 of disseminated mucinous neoplasms and were found in 8 (35%) of 23 low-grade mucinous neoplasms,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24925222
DOI: 10.1016/j.humpath.2014.04.018

Genes

GNAS
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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GNAS is frequently mutated in both low-grade and high-grade disseminated appendiceal mucinous neoplasms but does not affect survival.PMID 24925222Read ↗

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