Article
Comparative genomics of an IncA/C multidrug resistance plasmid from Escherichia coli and Klebsiella isolates from intensive care unit patients and the utility of whole-genome sequencing in health care settings.
Antimicrobial agents and chemotherapy - 1 Aug 2014
Hazen Tracy H, Zhao LiCheng, Boutin Mallory A, Stancil Angela, Robinson Gwen, Harris Anthony D, Rasko David A, Johnson J Kristie
Abstract excerpt
The IncA/C plasmids have been implicated for their role in the dissemination of β-lactamases, including gene variants that confer resistance to expanded-spectrum cephalosporins, which are often the treatment of last resort against multidrug-resistant, hospital-associated pathogens. A bla(FOX-5) g...
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