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Flotillin-1 expression in human clear-cell renal cell carcinoma is associated with cancer progression and poor patient survival

10 Jun 2014

Abstract excerpt

The present study was designed to elucidate the expression levels and the proliferative effect of flotillin-1, an integral membrane protein encoded by the FLOT1 gene, in human clear-cell renal cell carcinoma (RCC). Flotillin has been implicated in other types of cancer, but the role of flotillin in RCC has not been established. Immunohistochemistry and western blotting were used to determine FLOT1 protein...

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PMID: 24913320
DOI: 10.3892/mmr.2014.2310

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