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Article

Genetic variations of NLRP1: susceptibility in psoriasis.

The British journal of dermatology - 1 Dec 2014

Ekman A-K, Verma D, Fredrikson M, Bivik C, Enerbäck C

Abstract excerpt

BACKGROUND: NACHT, LRR and PYD domain-containing protein (NLRP)1 is part of the inflammasome multiprotein complex involved in the production of interleukin (IL)-1β and IL-18, two cytokines strongly implicated in psoriasis pathogenesis. Genetic variations in NLRP1 are associated with a predisposition for chronic inflammatory conditions. OBJECTIVES: The aim of the study was to investigate the role of genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24909542
DOI: 10.1111/bjd.13178

Genes

NLRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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