Article
Contribution of the latent transforming growth factor-β binding protein 2 gene to etiology of primary open angle glaucoma and pseudoexfoliation syndrome.
Molecular vision - 1 Jan 2013
Jelodari-Mamaghani Sahar, Haji-Seyed-Javadi Ramona, Suri Fatemeh, Nilforushan Naveed, Yazdani Shahin, Kamyab Kambiz, Elahi Elahe
Abstract excerpt
PURPOSE: To assess for the first time the possible contribution of latent transforming growth factor (TGF)-beta binding protein 2 (LTBP2), an extracellular matrix (ECM) protein that associates with fibrillin-1-containing microfibrils, to the etiology of primary open angle glaucoma (POAG) and pseudoexfoliation (PEX) syndrome. Mutations in LTBP2 have previously been shown to be the cause of primary congenital...
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