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A systems biology investigation of neurodegenerative dementia reveals a pivotal role of autophagy

1 Jan 2014

Abstract excerpt

BACKGROUND: Neurodegenerative dementia comprises chronic and progressive illnesses with major clinical features represented by progressive and permanent loss of cognitive and mental performance, including impairment of memory and brain functions. Many different forms of neurodegenerative dementia exist, but they are all characterized by death of specific subpopulation of neurons and accumulation of proteins in...

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PMID: 24908109
DOI: 10.1186/1752-0509-8-65

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