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Article

Enteropathogenic Escherichia coli dynamically regulates EGFR signaling in intestinal epithelial cells.

American journal of physiology. Gastrointestinal and liver physiology - 1 Aug 2014

Roxas Jennifer Lising, Ryan Katheryn, Vedantam Gayatri, Viswanathan V K

Abstract excerpt

The diarrheagenic pathogen enteropathogenic Escherichia coli (EPEC) dynamically modulates the survival of infected host intestinal epithelial cells. In the initial stages of infection, several prosurvival signaling events are activated in host cells. These include the phosphorylation of epidermal growth factor receptor (EGFR) and the consequent activation of the phosphatidylinositol-3 kinase/Akt pathway. While...

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Identifiers

PMID: 24904077
DOI: 10.1152/ajpgi.00312.2013
PMCID: PMC4121633

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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