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Article

The N-terminal domain of EspF induces host cell apoptosis after infection with enterohaemorrhagic Escherichia coli O157:H7.

PloS one - 1 Jan 2013

Zhao Suhui, Zhou Ying, Wang Chunhui, Yang Yu, Wu Xianbo, Wei Yao, Zhu Li, Zhao Wei, Zhang Qiwei, Wan Chengsong

Abstract excerpt

Enterohemorrhagic Escherichia coli (EHEC) employs a type III secretion system (TTSS) to export the translocator and effector proteins required for mucosal colonization. As an important bacterial effector protein in locus of enterocyte effacement four, the EspF protein causes F-actin filament aggregations to form attaching and effacing (A/E) lesions, and induces the destruction of brush-border microvilli and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23372831
DOI: 10.1371/journal.pone.0055164
PMCID: PMC3555930

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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