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Article

Association between macroorchidism and intelligence in FMR1 premutation carriers.

American journal of medical genetics. Part A - 1 Sept 2014

Lozano Reymundo, Summers Scott, Lozano Cristina, Mu Yi, Hessl David, Nguyen Danh, Tassone Flora, Hagerman Randi

Abstract excerpt

Characteristics of fragile X syndrome include macroorchidism and intellectual disability, which are associated with decreased FMRP levels. FMRP is highly expressed in many tissues, but primarily in the brain and testis. The relationship between these two characteristics has not previously been studied in the premutation or carrier state. To examine this among premutation carriers and a possible association with...

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Source

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Identifiers

PMID: 24903624
DOI: 10.1002/ajmg.a.36624
PMCID: PMC4332881

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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