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Article

Protective role of glutathione peroxidase 4 in laser-induced choroidal neovascularization in mice.

PloS one - 1 Jan 2014

Roggia Murilo Felix, Imai Hirotaka, Shiraya Tomoyasu, Noda Yasuo, Ueta Takashi

Abstract excerpt

PURPOSE: To evaluate the influence of glutathione peroxidase 4 (GPx4) expression in retinal pigment epithelium (RPE)/choroid tissue using a mouse model of laser-induced choroidal neovascularization (CNV). METHODS: In this study, GPx4+/-, GPx4+/+, and GPx4-overexpressing transgenic mice were creat...

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Identifiers

PMID: 24897344
DOI: 10.1371/journal.pone.0098864
PMCID: PMC4045803

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24897344-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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