Article
Ex vivo visualization of the mouse otoconial layer compared with micro-computed tomography.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology - 1 Feb 2015
Honda Keiji, Noguchi Yoshihiro, Kawashima Yoshiyuki, Takahashi Masatoki, Nishio Ayako, Kitamura Ken
Abstract excerpt
HYPOTHESIS: Micro-computed tomography (micro-CT) is useful for assessing the 3-dimensional (3D) morphology and age-related changes of the otoconial layer. BACKGROUND: Wriggle mouse Sagami (WMS) is a mutant of the plasma membrane Ca2+ ATPase type2 gene (Atp2b2) with deficits in the saccular otoconia. We examined the effectiveness of micro-CT in evaluating the otoconial layer of WMS and C57BL/6J mice. METHODS: Otic...
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