CD226 rs763361 is associated with the susceptibility to type 1 diabetes and greater frequency of GAD65 autoantibody in a Brazilian cohort.

doi:10.1155/2014/694948

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CD226 rs763361 is associated with the susceptibility to type 1 diabetes and greater frequency of GAD65 autoantibody in a Brazilian cohort.

Mediators of inflammation - 1 Jan 2014

Mattana Teresa Cristina Colvara, Santos Aritania Sousa, Fukui Rosa Tsuneshiro, Mainardi-Novo Debora Teixeira Oliveira, Costa Vinícius Silva, Santos Rosa Ferreira, Matioli Sergio Russo, da Silva Maria Elizabeth Rossi

Abstract excerpt

CD226 rs763361 variant increases susceptibility to type 1 diabetes (T1D) in Caucasians. There is no data about CD226 variants in the very heterogeneous Brazilian population bearing a wide degree of admixture. We investigated its association with T1D susceptibility, clinical phenotypes, and autoimmune manifestations (islet and extrapancreatic autoantibodies). Casuistry. 532 T1D patients and 594 controls in a...

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PMID: 24891767
DOI: 10.1155/2014/694948
PMCID: PMC4033476

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